Since his pioneering application of economic analysis to racial discrimination, Gary S. Becker has shown that an economic approach can provide a unified framework for understanding all human behavior. In a highly readable selection of essays Becker applies this approach to various aspects of human activity, including social interactions; crime and punishment; marriage, fertility, and the family; and "irrational" behavior. "Becker's highly regarded work in economics is most notable in the imaginative application of 'the economic approach' to a surprising (...) breadth of human activity. Becker's essays over the years have inevitably inspired a surge of research activity in testimony to the richness of his insights into human activities lying 'outside' the traditionally conceived economic markets. Perhaps no economist in our time has contributed more to expanding the area of interest to economists than Becker, and a number of these thought-provoking essays are collected in this book."—Choice Gary Becker was awarded the Nobel Prize in Economic Science in 1992. (shrink)

There is now a wealth of information that histone proteins play a primary role in the structural and transcriptional properties of chromatin, the protein‐DNA complex which constitutes the eukaryotic genome1, 2. In light of the crucial role of histones in cellular function, it is not surprising that their structural genes are found to be controlled in conjunction with the cell cycle, with the synthesis of most histones tightly coupled to nuclear DNA replication. The evidence suggests that this linkage between DNA (...) replication and histone synthesis involves the regulated adjustment of histone mRNA levels through both transcriptional and posttranscriptional control process. The possible mechanisms underlying these diverse control processes are described here. (shrink)

ABSTRACTThis paper examines the ontological status of individual substances; intuitive examples of such entities include particles and living organisms. My aim is to assess the ontological status of individual substances in the light of arguments for an ontology of [concrete] facts, often called states of affairs. Advocates of a fact ontology have argued that these factive entities are the ontologically fundamental beings. I will address the salient question of whether individual substances are reducible to, or eliminable in favor of, facts. (...) I will further address the question of whether individual substances, even if not reducible to facts, are nonetheless ontologically dependent upon facts in a way that undercuts the claim that some individual substances are ontologically fundamental. Finally, I will argue that a persuasive case for the claim that facts are what is ontologically fundamental has yet to be made. (shrink)

This volume is an invaluable resource for student and scholar alike.

I attempt to define the concept of ‘living organism’. Intuitively, a living organism is a substantial entity with a capacity for certain relevant activities. But biology has discovered that living organisms have a particular compositional or microstructural nature. This nature includes carbon-based macromolecules and water molecules. I argue that such living organisms belong to a natural kind of compound physical object, viz., carbon-based living organism. My definition of a living organism encompasses both the intuitively relevant activities and the empirically discovered (...) compositional nature. The definition is designed to deal with a variety of problem cases, e.g., viruses, proteinoid microspheres, sterile organisms, suspended animation cases, and living parts of organisms. (shrink)

Roderick Chisholm is a seminal figure in contemporary analytical metaphysics, epistemology, and philosophy of mind. The current healthy state of metaphysics and epistemology is in no small measure due to his influence and positive example. Chisholm has defended realism in metaphysics, foundationalism in epistemology, and the primacy of intentionality in the philosophy of mind. Throughout his long career at Brown, Chisholm was absorbed in the technical philosophical problems internal to this program. For example, his Socratic quests for the required definitions (...) are deservedly legendary. Still, this book is Chisholm's first attempt to provide a systematic exposition of his philosophical views, and it may be regarded as the definitive statement of the mature Chisholmian weltanschauung. The book is characterized by the virtues we have come to expect from this master of analytical philosophy: erudition, clarity, ingenuity, subtlety, technical virtuosity, and great depth. It covers a very large range of topics, in a small number of pages, in a style that is notably laconic. Such a book can be profitably read by those who are not advanced students of philosophy, but can be fully appreciated only by the most philosophically sophisticated. This important book should be read by all those who have a serious interest in metaphysics, epistemology, or philosophy of mind. (shrink)

The corporate glass ceiling continues to be a challenge for many organizations. However, women executives may be facing a second pane of obstruction – an expatriate glass ceiling – that prevents them from receiving the foreign management assignments and experience that is becoming increasing critical for promotion to upper management. The responsibility to break the expatriate glass ceiling lies with both female managers and the multinational corporations that utilize expatriates. In this paper, we propose pre-assignment, on-assignment, and post-assignment strategies for (...) breaking the expatriate glass ceiling. (shrink)

Near the end of Euripides' "Helen", Helen reportedly exhorts the Greek troops to rescue her Egyptian foes: "Where is the glory of Troy ? Show it to these barbarians" . Helen's rallying cry serves as a point of departure for investigating the nature and status of kleos in a play which invites reframing her question: Where, indeed, is the glory of Troy if the report of Helen's abduction by Paris is untrue? The drama deconstructs the notion of a unitary, transcendent (...) meaning of "kleos" by demonstrating the slippage between its two root-meanings in Homer as "immortal fame," legitimated by the gods, and as mere "report" or "rumor." A diminution of the status of the proper name runs in parallel with this slippage between the two senses of "kleos": the heroic name loses its privileged status as a stable, transparent sign of character and becomes instead a signifier vulnerable to dissemination . As a vehicle of deception, Helen's phantom-twin becomes a figure for the polysemy of the signifier, both visual and linguistic. The phantom's substitution for Helen also highlights her symbolic role as a marker of men's status in a competitive system of exchange. If the play presents Helen as a continual object of men's attempts to capture her in song as well as in war, it presents heroic kleos as an equally insecure possession, insofar as it is always contingent on the "report" of others. Indeed, Helen becomes a metaphor for the duplicity inherent in the mimetic process by which fame is transmitted. That "kleos" turns out to have been a dangerously deceptive signifier is a lesson of more than literary interest for the Athenians watching Euripides' "Helen" -the forces of the Sicilian expedition had been annihilated only a year earlier. (shrink)

Drawing inspiration from Aristotle's biological writings, I attempt to elucidate what it is for something to be alive by providing illuminating logically necessary and sufficient conditions for something's being a living thing in the broadest sense. I then propose a related account of identity conditions for carbon‐based living organisms.

Theories of language production propose that utterances are constructed by a mechanism that separates linguistic content from linguistic structure, Linguistic content is retrieved from the mental lexicon, and is then inserted into slots in linguistic structures or frames. Support for this kind of model at the phonological level comes from patterns of phonological speech errors. W present an alternative account of these patterns using a connectionist or parallel distributed proceesing (PDP) model that learns to produce sequences of phonological features. The (...) model's errors exhibit some of the properties of human speech errors, specifically, properties that have been attributed to the action of phonological rules, frames, or other structural generalizations. (shrink)

Use of electronic health records within clinical encounters is increasingly pervasive. The digital record allows for data storage and sharing to facilitate patient care, billing, research, patient communication and quality-of-care improvement—all at once. However, this multifunctionality is also one of the main reasons care providers struggle with the EHR. These problems have often been described but are rarely approached from a philosophical point of view. We argue that a postphenomenological case study of the EHR could lead to more in-depth insights. (...) We will focus on two concepts—transparency and multistability—and translate them to the specific situation of the EHR. Transparency is closely related to an embodiment relation in which the user becomes less aware of the technology: it fades into the background, becoming a means of experience. A second key concept is that of multistability, referring to how a technology can serve multiple purposes or can have different meanings in different contexts. The EHR in this sense is multistable by design. Future EHR design could incorporate multistable information differently, allowing the provider to focus on patient care when interacting with the EHR. Moreover we argue that the use of the EHR in the daily workflow should become more transparent, while awareness of the computer in the specific context of the patient-provider relationship should increase. (shrink)

Theories of language production have long been expressed as connectionist models. We outline the issues and challenges that must be addressed by connectionist models of lexical access and grammatical encoding, and review three recent models. The models illustrate the value of an interactive activation approach to lexical access in production, the need for sequential output in both phonological and grammatical encoding, and the potential for accounting for structural effects on errors and structural priming from learning.

This book revives a neglected but important topic in philosophy: the nature of substance. The belief that there are individual substances, for example, material objects and persons, is at the core of our common-sense view of the world yet many metaphysicians deny the very coherence of the concept of substance. The authors develop an account of what an individual substance is in terms of independence from other beings. In the process many other important ontological categories are explored: property, event, space, (...) time. The authors show why alternative theories of substance fail, and go on to defend the intelligibility of interacting spiritual and material substances. (shrink)

This chapter contains section titled: Substance Among Other Categories Substance and Independence Spinoza's Divine Substance.

Substance has been a leading idea in the history of Western philosophy. _Joshua Hoffman and Gary S. Rosenkrantz_ explain the nature and existence of individual substances, including both living things and inanimate objects. Specifically written for students new to this important and often complex subject, _Substance_ provides both the historical and contemporary overview of the debate. Great Philosophers of the past, such as Aristotle, Descartes, Spinoza, Leibnitz, Locke, and Berkeley were profoundly interested in the concept of substance. And, the (...) authors argue, a belief in the existence of substances is an integral part of our everyday world view. But what constitutes substance? Was Aristotle right to suggest that artefacts like tables and ships don't really exist? _Substance: Its Nature and Existence_ is one of the first non-technical, accessible guides to this central problem and will be of great use to students of metaphysics and philosophy. (shrink)

Interactive theories of lexical retrieval in language production assume that activation cascades from earlier to later processing levels, and feeds back in the reverse direction. This commentary invites Pickering & Garrod (P&G) to consider whether cascading and feedback can be seen as a form of forwarding modeling within a hierarchical production system.

Whenever the name Edmund Husserl appears in the context of nursing research, what correctly comes to mind is the phenomenological approach to qualitative methodology. Husserl is not only considered the founder of phenomenology, but his broad concept development also contributed to the demise of positivism and inspired fruitful approaches to the social sciences. In this spirit of inspiration, it must be expressed that Husserl's theory of wholes and parts, and particularly his differentiation of parts into ‘pieces’ and ‘moments’, is very (...) helpful in guiding the selection of research methods across the board in nursing science. The purpose of this paper is to highlight a frame of reference for nursing researchers to use in examining the essential nature of that which is being studied. This frame of reference is the Husserlian philosophy of ‘pieces’ and ‘moments’ in relation to the whole. ‘Pieces’ are independent parts of the whole that are subject to isolability in study, whereas ‘moments’ are nonindependent parts, which cannot be detached, presented, or studied apart from the whole. The intent is to propose this frame of reference as a philosophical base from which nursing researchers may better select among paradigms and methodological approaches in regard to the essential nature (‘pieces’ or ‘moments’) of that which they are researching. (shrink)

This chapter contains section titled: Notes Bibliography.

This chapter contains section titled: Omniscience as Maximal Knowledge The Analysis of Omniscience Divine Foreknowledge and Human Freedom.